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Merck

SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

同義詞:
PAI, PAI-1, PAI1, PLANH1
物種:
UniProtKB ID:
基因 ID:
  • Human(5054) Summary: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(18787) serine (or cysteine) peptidase inhibitor, clade E, member 1
  • Rat(24617) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • cow(281375) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Zebrafish(100136840) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic guinea pig(100725387) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • naked mole-rat(101703903) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Domestic Rabbit(100009588) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • dog(403476) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic cat(100127105) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

Custom & Knockdown Gene Products

ELISA

產品編號
描述
物種
人 PAI-1 ELISA 试剂盒, for serum, plasma, cell culture supernatant.,
物種
human

Antibodies

產品編號
描述
物種活性
應用
Anti-PAI-1 Mouse mAb (MA-33B8), liquid, ≥90% (SDS-PAGE), clone MA-33B8,
物種活性
human, rabbit
應用
Anti-PAI-1 (Ab-1) Mouse mAb (2), lyophilized, clone 2, Calbiochem®,
物種活性
human
應用
Anti-SerPINE1 (AB1) antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, human, mouse, pig, rabbit, rat, sheep
應用
immunohistochemistry
western blot
Anti-SerPINE1 (AB2) antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, horse, human, pig, rabbit, rat, sheep
應用
western blot

Proteins

產品編號
描述
物種
血纤维蛋白溶酶原激活物抑制剂1(PAI-1) 人, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
物種
human