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Merck

SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

同義詞:
CERIII, CIAT, EIEE13, MED, NaCh6, Nav1.6, PN4
物種:
UniProtKB ID:
基因 ID:
  • Human(6334) Summary: This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(20273) sodium channel, voltage-gated, type VIII, alpha
  • Rat(29710) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(100857835) sodium channel, voltage gated, type VIII, alpha subunit
  • dog(477604) sodium channel, voltage gated, type VIII, alpha subunit
  • Horse(100052777) sodium channel, voltage gated, type VIII, alpha subunit
  • cow(537277) sodium channel, voltage gated, type VIII, alpha subunit
  • naked mole-rat(101711868) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic guinea pig(100734003) sodium channel, voltage gated, type VIII, alpha subunit
  • sheep(101113744) sodium channel, voltage gated, type VIII, alpha subunit
  • domestic cat(101096578) sodium channel, voltage gated, type VIII, alpha subunit
  • chicken(426869) sodium channel, voltage gated, type VIII, alpha subunit

Custom & Knockdown Gene Products

Antibodies

產品編號
描述
物種活性
應用
抗-SCN8A钠通道抗体, Chemicon®, from rabbit,
物種活性
mouse, rat
應用
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-SCN8A antibody produced in mouse, clone 4G7, purified immunoglobulin, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

western blot
Anti-Sodium Channel PN4 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物種活性
rat
應用
western blot
Pan单克隆抗 钠通道 小鼠抗, ~1 mg/mL, clone K58/35, purified immunoglobulin,
物種活性
mammals
應用
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

產品編號
描述
物種
利多卡因, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
利多卡因, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
利多卡因 盐酸盐 一水合物, solid,
物種
human
普鲁卡因 盐酸盐, ≥97%,
物種
human
利多卡因, United States Pharmacopeia (USP) Reference Standard,
物種
human