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Merck

SAFB

scaffold attachment factor B

同義詞:
HAP, HET, SAF-B1, SAFB1
物種:
Human SAFB (6294), Mouse Safb (224903), Rat Safb (64196), chicken SAFB (426047), Zebrafish safb (321979), domestic guinea pig Safb (100718986), naked mole-rat Safb (101713322), domestic cat SAFB (101092244), cow SAFB (539785), dog SAFB (485028)
UniProtKB ID:
Q15424, A0AV56, B7Z5B6, B7ZLP6, F5H0H3, O60406, Q59HH8
基因 ID:
  • Human(6294) Summary: This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]
  • Mouse(224903) scaffold attachment factor B
  • Rat(64196) scaffold attachment factor B
  • chicken(426047) scaffold attachment factor B
  • Zebrafish(321979) scaffold attachment factor B
  • domestic guinea pig(100718986) scaffold attachment factor B
  • naked mole-rat(101713322) scaffold attachment factor B
  • domestic cat(101092244) scaffold attachment factor B
  • cow(539785) scaffold attachment factor B
  • dog(485028) scaffold attachment factor B

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Antibodies

產品編號
描述
物種活性
應用
SAB2702149
Monoclonal Anti-SAFB antibody produced in mouse, ,
物種活性
human, mouse
應用
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
05-588
Anti-HET/SAF-B Antibody, clone 6F7, clone 6F7, Upstate®, from mouse,
物種活性
human
應用
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot