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Merck

RNF20

ring finger protein 20, E3 ubiquitin protein ligase

同義詞:
BRE1, BRE1A, hBRE1
物種:
UniProtKB ID:
基因 ID:
  • Human(56254) Summary: The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]
  • Mouse(109331) ring finger protein 20
  • Rat(313216) ring finger protein 20, E3 ubiquitin protein ligase
  • Zebrafish(402838) ring finger protein 20, E3 ubiquitin protein ligase
  • domestic cat(101097522) ring finger protein 20, E3 ubiquitin protein ligase
  • cow(513326) ring finger protein 20
  • dog(474788) ring finger protein 20, E3 ubiquitin protein ligase
  • chicken(427310) ring finger protein 20, E3 ubiquitin protein ligase
  • naked mole-rat(101711656) ring finger protein 20, E3 ubiquitin protein ligase
  • domestic guinea pig(100717191) ring finger protein 20, E3 ubiquitin protein ligase
  • Domestic Rabbit(100340973) ring finger protein 20, E3 ubiquitin protein ligase
  • Horse(100054384) ring finger protein 20, E3 ubiquitin protein ligase
  • sheep(101121065) ring finger protein 20, E3 ubiquitin protein ligase

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Antibodies

產品編號
描述
物種活性
應用
Anti-RNF20 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
immunofluorescence
western blot

Proteins

產品編號
描述
物種
RNF20 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
物種
human