PTPRC
protein tyrosine phosphatase, receptor type, C
同義詞:
B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
物種:
Human PTPRC (5788), Mouse Ptprc (19264), Rat Ptprc (24699), Zebrafish ptprc (559154), chicken PTPRC (386580), domestic cat PTPRC (101097123), Horse PTPRC (100061950), dog PTPRC (490255), sheep PTPRC (101102917), cow PTPRC (407152) ...更多
UniProtKB ID:
基因 ID:
- Human(5788) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
- Mouse(19264) protein tyrosine phosphatase, receptor type, C
- Rat(24699) protein tyrosine phosphatase, receptor type, C
- Zebrafish(559154) protein tyrosine phosphatase, receptor type, C
- chicken(386580) protein tyrosine phosphatase, receptor type, C
- domestic cat(101097123) protein tyrosine phosphatase, receptor type, C
- Horse(100061950) protein tyrosine phosphatase, receptor type, C
- dog(490255) protein tyrosine phosphatase, receptor type, C
- sheep(101102917) protein tyrosine phosphatase, receptor type, C
- cow(407152) protein tyrosine phosphatase, receptor type, C
- Domestic Rabbit(100358807) protein tyrosine phosphatase, receptor type, C
- naked mole-rat(101710515) protein tyrosine phosphatase, receptor type, C
- domestic guinea pig(100730564) protein tyrosine phosphatase, receptor type, C
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Antibodies
產品編號
描述
物種活性
應用
Anti-CD45 Antibody, clone IBL-5/25, clone IBL-5/25, from rat,
物種活性
mouse
應用
flow cytometry
immunohistochemistry
immunohistochemistry
抗-CD45 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
抗-CD45 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
immunohistochemistry
Anti-CD45 antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM291, purified immunoglobulin,
物種活性
human
應用
immunohistochemistry
western blot
western blot