PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
HC9, HsT17706, PSC9
Human PSMA4 (5685), Mouse Psma4 (26441), Rat Psma4 (29671), naked mole-rat Psma4 (101701639), cow PSMA4 (510423), domestic cat PSMA4 (101084967), chicken PSMA4 (415357), Zebrafish psma4 (326687), dog PSMA4 (475132), domestic guinea pig Psma4 (100730420)
- Human(5685) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(26441) proteasome (prosome, macropain) subunit, alpha type 4
- Rat(29671) proteasome (prosome, macropain) subunit, alpha type 4
- naked mole-rat(101701639) proteasome (prosome, macropain) subunit, alpha type, 4
- cow(510423) proteasome (prosome, macropain) subunit, alpha type, 4
- domestic cat(101084967) proteasome (prosome, macropain) subunit, alpha type, 4
- chicken(415357) proteasome (prosome, macropain) subunit, alpha type, 4
- Zebrafish(326687) proteasome (prosome, macropain) subunit, alpha type, 4
- dog(475132) proteasome (prosome, macropain) subunit, alpha type, 4
- domestic guinea pig(100730420) proteasome (prosome, macropain) subunit, alpha type, 4
- sheep(101122816) proteasome (prosome, macropain) subunit, alpha type, 4
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