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Merck

PSMA4

proteasome (prosome, macropain) subunit, alpha type, 4

同義詞:
HC9, HsT17706, PSC9
物種:
UniProtKB ID:
基因 ID:
  • Human(5685) Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(26441) proteasome (prosome, macropain) subunit, alpha type 4
  • Rat(29671) proteasome (prosome, macropain) subunit, alpha type 4
  • naked mole-rat(101701639) proteasome (prosome, macropain) subunit, alpha type, 4
  • cow(510423) proteasome (prosome, macropain) subunit, alpha type, 4
  • domestic cat(101084967) proteasome (prosome, macropain) subunit, alpha type, 4
  • chicken(415357) proteasome (prosome, macropain) subunit, alpha type, 4
  • Zebrafish(326687) proteasome (prosome, macropain) subunit, alpha type, 4
  • dog(475132) proteasome (prosome, macropain) subunit, alpha type, 4
  • domestic guinea pig(100730420) proteasome (prosome, macropain) subunit, alpha type, 4
  • sheep(101122816) proteasome (prosome, macropain) subunit, alpha type, 4

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