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Merck

POLR2A

polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

同義詞:
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
物種:
UniProtKB ID:
基因 ID:
  • Human(5430) Summary: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
  • Mouse(20020) polymerase (RNA) II (DNA directed) polypeptide A
  • Rat(363633) polymerase (RNA) II (DNA directed) polypeptide A
  • cow(282312) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • naked mole-rat(101725588) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • dog(479483) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • Zebrafish(553347) polymerase (RNA) II (DNA directed) polypeptide A
  • sheep(100144762) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • domestic cat(101098500) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
  • domestic guinea pig(100734232) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa

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Antibodies

產品編號
描述
物種活性
應用
Anti-RNA Polymerase II Antibody, CTD Antibody, clone 8WG16, clone 8WG16, from mouse,
物種活性
human, yeast
應用
dot blot
immunoprecipitation (IP)

inhibition assay

western blot
Monoclonal Anti-phospho-RNA polymerase II CTD (pSer2) antibody produced in rat, clone 3E7C7, purified from hybridoma cell culture,
物種活性
應用
flow cytometry
immunofluorescence

western blot
Goat anti-RNA Polymerase II Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物種活性
human, mouse
應用
immunoprecipitation (IP)
western blot
Anti-RNA Polymerase II Antibody, clone ARNA-3, ascites fluid, clone ARNA-3, Chemicon®,
物種活性
drosophila, human, kangaroo
應用
immunohistochemistry
western blot
Monoclonal Anti-POLR2A, (N-terminal) antibody produced in mouse, clone IF17, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot

Proteins

產品編號
描述
物種
RNA聚合酶II,C端域,GST标记 人, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
物種
human
RNA Polymerase II, C-terminal human, recombinant, expressed in E. coli, ≥85% (SDS-PAGE),
物種
human

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human POLR2A,
物種
human