PLCG1
phospholipase C, gamma 1
同義詞:
NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1
物種:
Human PLCG1 (5335), Mouse Plcg1 (18803), Rat Plcg1 (25738), naked mole-rat Plcg1 (101705192), chicken PLCG1 (419175), dog PLCG1 (485874), Zebrafish plcg1 (373867), domestic cat PLCG1 (101092925), cow PLCG1 (281987), domestic guinea pig Plcg1 (100716986)
UniProtKB ID:
基因 ID:
- Human(5335) Summary: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(18803) phospholipase C, gamma 1
- Rat(25738) phospholipase C, gamma 1
- naked mole-rat(101705192) phospholipase C, gamma 1
- chicken(419175) phospholipase C, gamma 1
- dog(485874) phospholipase C, gamma 1
- Zebrafish(373867) phospholipase C, gamma 1
- domestic cat(101092925) phospholipase C, gamma 1
- cow(281987) phospholipase C, gamma 1
- domestic guinea pig(100716986) phospholipase C, gamma 1
- sheep(101103341) phospholipase C, gamma 1
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Antibodies
產品編號
描述
物種活性
應用
Anti-PLCγ-1 Antibody, Upstate®, from mouse,
物種活性
bovine, human, mouse, rabbit, rat
應用
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-phospho-PLCG1 (pTyr783) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
western blot
Monoclonal Anti-PLCG1 antibody produced in mouse, clone 2A2, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
抗-磷酸化-PLCG1 (pTyr783) 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PLCγ-1 Antibody, clone B-6-4, clone B-6-4, 1 mg/mL, Upstate®,
物種活性
bovine, human, mouse, rabbit, rat
應用
immunoprecipitation (IP)
western blot
western blot