PLAUR
plasminogen activator, urokinase receptor
同義詞:
CD87, U-PAR, UPAR, URKR
物種:
Human PLAUR (5329), Mouse Plaur (18793), Rat Plaur (50692), dog PLAUR (476446), Horse PLAUR (100033904), domestic cat PLAUR (101091240), sheep PLAUR (100302564), cow PLAUR (281983), domestic guinea pig Plaur (100715207), naked mole-rat Plaur (101705929)
UniProtKB ID:
基因 ID:
- Human(5329) Summary: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
- Mouse(18793) plasminogen activator, urokinase receptor
- Rat(50692) plasminogen activator, urokinase receptor
- dog(476446) plasminogen activator, urokinase receptor
- Horse(100033904) plasminogen activator, urokinase receptor
- domestic cat(101091240) plasminogen activator, urokinase receptor
- sheep(100302564) plasminogen activator, urokinase receptor
- cow(281983) plasminogen activator, urokinase receptor
- domestic guinea pig(100715207) plasminogen activator, urokinase receptor
- naked mole-rat(101705929) plasminogen activator, urokinase receptor
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Antibodies
產品編號
描述
物種活性
應用
单克隆抗 PLAUR/uPAR 小鼠抗, clone PL231, purified from hybridoma cell culture,
物種活性
canine, human, monkey, mouse, rat
應用
immunofluorescence
western blot
western blot