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Merck

PDGFRB

platelet-derived growth factor receptor, beta polypeptide

同義詞:
CD140B, IBGC4, IMF1, JTK12, PDGFR, PDGFR-1, PDGFR1
物種:
UniProtKB ID:
基因 ID:
  • Human(5159) Summary: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008]
  • Mouse(18596) platelet derived growth factor receptor, beta polypeptide
  • Rat(24629) platelet derived growth factor receptor, beta polypeptide
  • domestic guinea pig(100726506) platelet-derived growth factor receptor, beta polypeptide
  • naked mole-rat(101721151) platelet-derived growth factor receptor, beta polypeptide
  • Zebrafish(559529) platelet-derived growth factor receptor beta
  • chicken(770488) platelet-derived growth factor receptor, beta polypeptide
  • dog(442985) platelet-derived growth factor receptor, beta polypeptide
  • domestic cat(101084600) platelet-derived growth factor receptor, beta polypeptide
  • cow(527165) platelet-derived growth factor receptor, beta polypeptide
  • Domestic Rabbit(100342872) platelet-derived growth factor receptor, beta polypeptide
  • sheep(101122783) platelet-derived growth factor receptor, beta polypeptide

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ELISA

產品編號
描述
物種
人PDGF Rβ ELISA试剂盒, for serum, plasma, cell culture supernatant and urine,
物種
human
磷酸酪氨酸PDGFRB /血小板源性生长因子受体β ELISA试剂盒, ,
物種
human

Antibodies

產品編號
描述
物種活性
應用
Anti-PDGF Receptor β antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-PDGFR Beta Antibody, from rabbit, purified by affinity chromatography,
物種活性
bovine, canine, human, mouse
應用
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-PDGFR β antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

immunohistochemistry

western blot
抗PDGFR抗体,克隆CH-3, clone CH-3, from mouse,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot
Monoclonal Anti-PDGFRB antibody produced in mouse, clone 4C12, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunoprecipitation (IP)

proximity ligation assay

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
2-苯基苯并咪唑, 97%,
物種
human
伊马替尼, ,
物種
human
PD 173074, ≥96% (HPLC), powder,
物種
mouse, human
SU 5416, ≥98% (HPLC),
物種
human, mouse
酪氨酸激酶抑制剂A9, solid,
物種
mouse, human

Proteins

產品編號
描述
物種
PDGFRβ Protein, active, 50 µg, Active, recombinant human PDGF Receptor β, residues 557-end, containing an N-terminal His6-tag, for use in Kinase Assays.,
物種
human