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Merck

PCDHA4

protocadherin alpha 4

同義詞:
CNR1, CNRN1, CRNR1, PCDH-ALPHA4
物種:
UniProtKB ID:
基因 ID:
  • Human(56144) Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
  • Mouse(12936) protocadherin alpha 4
  • Rat(116741) protocadherin alpha 4
  • cow(616099) protocadherin alpha 4
  • dog(607212) protocadherin alpha 4
  • dog(607199) protocadherin alpha 4
  • chicken(497214) protocadherin alpha 4
  • domestic cat(101092733) protocadherin alpha 4
  • domestic guinea pig(100713594) protocadherin alpha 4

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Antibodies

產品編號
描述
物種活性
應用
Anti-PCDHA4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
western blot
Anti-PCDHA4 (AB2) antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
應用
western blot