LILRB2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
同義詞:
CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10
物種:
UniProtKB ID:
基因 ID:
- Human(10288) Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- dog(484309) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
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Antibodies
產品編號
描述
物種活性
應用
Monoclonal Anti-LILRB2 antibody produced in mouse, clone 1D4, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
western blot