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Merck

HTR4

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

同義詞:
5-HT4, 5-HT4R
物種:
Human HTR4 (3360), Mouse Htr4 (15562), Rat Htr4 (25324), Horse HTR4 (100034053), domestic cat HTR4 (101088723), sheep HTR4 (101117928), cow HTR4 (317708), domestic guinea pig Htr4 (100135548), chicken HTR4 (416150), dog HTR4 (489198)
UniProtKB ID:
Q13639, Q546Q1, Q684M0, Q712M9, Q96KH9, Q96KI0, Q9H199, Q9NY73
基因 ID:
  • Human(3360) Summary: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
  • Mouse(15562) 5 hydroxytryptamine (serotonin) receptor 4
  • Rat(25324) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • Horse(100034053) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • domestic cat(101088723) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • sheep(101117928) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • cow(317708) 5-hydroxytryptamine (serotonin) receptor 4
  • domestic guinea pig(100135548) 5 hydroxytryptamine (serotonin) receptor 4
  • chicken(416150) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • dog(489198) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • naked mole-rat(101707865) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

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Small Molecule - Agonist

產品編號
描述
物種
SML1504
Tegaserod maleate, ≥98% (HPLC),
物種
human
32473
甲氧氯普胺, VETRANAL®, analytical standard,
物種
human
M1824990
甲氧氯普胺, European Pharmacopoeia (EP) Reference Standard,
物種
human
BP357
甲氧氯普胺 盐酸盐, British Pharmacopoeia (BP) Reference Standard,
物種
human
M0763
甲氧氯普胺 盐酸盐, solid,
物種
human

Small Molecule - Allosteric Modulator

產品編號
描述
物種
D9190
DCEBIO, ≥98% (HPLC), solid,
物種
human

Small Molecule - Antagonist

產品編號
描述
物種
S3313
SB-204070 盐酸盐, solid, ≥97% (HPLC),
物種
human
32473
甲氧氯普胺, VETRANAL®, analytical standard,
物種
human
G5918
GR 113808, ≥98% (HPLC), solid,
物種
rat, human
M1824990
甲氧氯普胺, European Pharmacopoeia (EP) Reference Standard,
物種
human
BP357
甲氧氯普胺 盐酸盐, British Pharmacopoeia (BP) Reference Standard,
物種
human

Antibodies

產品編號
描述
物種活性
應用
SAB4501480
Anti-5-HT-4 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
western blot
SAB2101109
Anti-HTR4 antibody produced in rabbit, affinity isolated antibody,
物種活性
dog, human, rabbit
應用
western blot

Small Molecule - Blocker

產品編號
描述
物種
T3146
三甲丙咪嗪标准液 马来酸盐, ≥98% (TLC), powder,
物種
human
Z101
泽麦定 二盐酸盐, solid,
物種
human

Small Molecule - Inhibitor

產品編號
描述
物種
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
物種
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
物種
human
F132
氟西汀 盐酸盐, solid,
物種
human
S6319
盐酸舍曲林 盐酸盐, ≥98% (HPLC),
物種
human
R0875
利血平, ,
物種
human

Small Molecule - Ligand

產品編號
描述
物種
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
物種
human

Small Molecule - Metabolite

產品編號
描述
物種
H8876
5-羟基吲哚-3-乙酸, ≥98% (HPLC), crystalline,
物種
human

Small Molecule - Precursor

產品編號
描述
物種
H9772
5-羟基L-色氨酸, powder,
物種
human