跳轉至內容
Merck

HRAS

Harvey rat sarcoma viral oncogene homolog

同義詞:
C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
物種:
Human HRAS (3265), Rat Hras (293621), dog HRAS (403735), cow HRAS (100298939), naked mole-rat Hras (101716053), chicken HRAS (396229), domestic guinea pig Hras (100735038), sheep HRAS (101104357)
UniProtKB ID:
P01112, B5BUA0, Q14080, Q6FHV9, Q9BR65, Q9UCE2
基因 ID:
  • Human(3265) Summary: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Rat(293621) Harvey rat sarcoma virus oncogene
  • dog(403735) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • cow(100298939) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • naked mole-rat(101716053) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • chicken(396229) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • domestic guinea pig(100735038) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • sheep(101104357) v-Ha-ras Harvey rat sarcoma viral oncogene homolog

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Small Molecule - Antagonist

產品編號
描述
物種
G8877
鸟苷5′-三磷酸 钠盐 水合物, ≥95% (HPLC), powder,
物種
human
I0879
肌苷 5′-三磷酸盐 三钠盐, ≥95%,
物種
human
G3776
鸟苷5′-三磷酸 钠盐 溶液, HPLC purified, aqueous solution for RNA polymerase transcription,
物種
human
D7409
2′,3′-双脱氧鸟苷 5′-三磷酸 钠盐, ≥90% (HPLC),
物種
human
E7781
Erastin, ≥98% (HPLC),
物種
mouse, rat, human

Antibodies

產品編號
描述
物種活性
應用
OP23
Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1), liquid, clone F235-1.7.1, Calbiochem®,
物種活性
human, mouse, rat
應用
04-775
抗-Ha-Ras抗体（克隆MC57，兔单克隆）, culture supernatant, clone MC57, from rabbit,
物種活性
human, mouse, rat
應用
western blot
SAB4301113
Anti-RAS antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
western blot
SAB1405964
Anti-HRAS antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
proximity ligation assay
western blot
MAB3291
Anti-H-Ras Antibody, clone 7D7.2, clone 7D7.2, Chemicon®, from mouse,
物種活性
human, mouse, rat
應用
ELISA
western blot