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Merck

HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

同義詞:
HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
物種:
UniProtKB ID:
基因 ID:
  • Human(3091) Summary: This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
  • Mouse(15251) hypoxia inducible factor 1, alpha subunit
  • Rat(29560) hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  • dog(480348) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  • domestic guinea pig(100713113) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  • naked mole-rat(101715845) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  • Domestic Rabbit(100009579) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  • sheep(443519) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  • cow(281814) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  • domestic cat(101083686) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
  • chicken(374177) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

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ELISA

產品編號
描述
物種
Human HIF-1 alpha ELISA Kit, for cell culture supernatants, plasma, and serum samples,
物種
human

Antibodies

產品編號
描述
物種活性
應用
抗-HIF1A 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
immunohistochemistry
抗缺氧诱导因子1 α 抗体,克隆 H1α67, clone H1alpha67, Chemicon®, from mouse,
物種活性
ferret, human, mouse, rat
應用
electrophoretic mobility shift assay
immunohistochemistry

immunoprecipitation (IP)

western blot
抗-HIF1A 兔抗, ,
物種活性
bovine, human, mouse, rat
應用
ChIP
immunocytochemistry

immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-HIF-1 alpha antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM242, purified immunoglobulin,
物種活性
human
應用
immunohistochemistry
western blot
抗 HIF-1α 单克隆抗体 小鼠抗, clone ESEE122, 1 mg/mL, purified immunoglobulin,
物種活性
bovine, human, mouse, rat
應用
ELISA
immunocytochemistry

immunofluorescence

immunohistochemistry

western blot

Proteins

產品編號
描述
物種
HIF-1 α, C-terminal activation domain (776-826 human, recombinant, expressed in E. coli, ≥85% (SDS-PAGE),
物種
human
HIF-1 α N-terminal activation domain (530-698) human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
物種
human

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human HIF1A,
物種
human
MISSION® esiRNA, targeting mouse Hif1a,
物種
mouse