FBXO32
F-box protein 32
Fbx32, MAFbx
Human FBXO32 (114907), Mouse Fbxo32 (67731), Rat Fbxo32 (171043), domestic cat FBXO32 (101083398), Horse FBXO32 (100057506), Zebrafish fbxo32 (393891), chicken FBXO32 (420343), domestic guinea pig Fbxo32 (100726187), naked mole-rat Fbxo32 (101718496), sheep FBXO32 (100142676) ...更多
- Human(114907) Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
- Mouse(67731) F-box protein 32
- Rat(171043) F-box protein 32
- domestic cat(101083398) F-box protein 32
- Horse(100057506) F-box protein 32
- Zebrafish(393891) F-box protein 32
- chicken(420343) F-box protein 32
- domestic guinea pig(100726187) F-box protein 32
- naked mole-rat(101718496) F-box protein 32
- sheep(100142676) F-box protein 32
- cow(513776) F-box protein 32
- Domestic Rabbit(100356177) F-box protein 32
- dog(475091) F-box protein 32
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Antibodies
Anti-Fbx32/FBOX32 antibody produced in rabbit, ,
mouse, rat
immunohistochemistry
western blot
western blot
Anti-FBXO32 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
human
western blot
Anti-FBXO32 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
human
ELISA
western blot
western blot