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Merck

ESPL1

extra spindle pole bodies homolog 1 (S. cerevisiae)

同義詞:
ESP1, SEPA
物種:
UniProtKB ID:
基因 ID:
  • Human(9700) Summary: Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]
  • Mouse(105988) extra spindle poles-like 1 (S. cerevisiae)
  • Rat(315330) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • chicken(425536) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • Zebrafish(797406) extra spindle poles like 1
  • domestic guinea pig(100733255) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • naked mole-rat(101723260) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • Domestic Rabbit(100356105) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • domestic cat(101084118) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • Horse(100063779) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • cow(506740) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • sheep(101105898) extra spindle pole bodies homolog 1 (S. cerevisiae)
  • dog(607879) extra spindle pole bodies homolog 1 (S. cerevisiae)

Custom & Knockdown Gene Products

Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-ESPL1 antibody produced in mouse, clone 6H6, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunohistochemistry

western blot