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Merck

EIF2AK3

eukaryotic translation initiation factor 2-alpha kinase 3

同義詞:
PEK, PERK, WRS
物種:
UniProtKB ID:
基因 ID:
  • Human(9451) Summary: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Jan 2010]
  • Mouse(13666) eukaryotic translation initiation factor 2 alpha kinase 3
  • Rat(29702) eukaryotic translation initiation factor 2 alpha kinase 3
  • Horse(100066488) eukaryotic translation initiation factor 2-alpha kinase 3
  • domestic cat(101095973) eukaryotic translation initiation factor 2-alpha kinase 3
  • cow(535820) eukaryotic translation initiation factor 2-alpha kinase 3
  • Zebrafish(559564) eukaryotic translation initiation factor 2-alpha kinase 3
  • dog(475756) eukaryotic translation initiation factor 2-alpha kinase 3
  • chicken(422930) eukaryotic translation initiation factor 2-alpha kinase 3
  • sheep(101110042) eukaryotic translation initiation factor 2-alpha kinase 3
  • domestic guinea pig(100725836) eukaryotic translation initiation factor 2-alpha kinase 3
  • naked mole-rat(101713561) eukaryotic translation initiation factor 2-alpha kinase 3

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Antibodies

產品編號
描述
物種活性
應用
Anti-PERK Antibody, clone 4F6.1, clone 4F6.1, from mouse,
物種活性
human
應用
immunohistochemistry
western blot
抗-磷酸化-PEK/PERK (pThr981) 兔抗, affinity isolated antibody,
物種活性
human
應用
immunohistochemistry
Anti-PERK (N-terminal) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
mouse, rat
應用
western blot
抗-PERK(C端) 兔抗, IgG fraction of antiserum, buffered aqueous solution,
物種活性
human, mouse, rat
應用
western blot

Proteins

產品編號
描述
物種
EIF2AK3 (563-1115), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human
PEK, active, ,
物種
human
PEK Protein, active, 10 µg, ,
物種
human

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human EIF2AK3, AC104134.2,
物種
human