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Merck

EIF2AK2

eukaryotic translation initiation factor 2-alpha kinase 2

同義詞:
EIF2AK1, PKR, PRKR
物種:
UniProtKB ID:
基因 ID:
  • Human(5610) Summary: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
  • Mouse(19106) eukaryotic translation initiation factor 2-alpha kinase 2
  • Rat(54287) eukaryotic translation initiation factor 2-alpha kinase 2
  • Zebrafish(100001092) eukaryotic translation initiation factor 2-alpha kinase 2
  • domestic guinea pig(100717384) eukaryotic translation initiation factor 2-alpha kinase 2
  • Domestic Rabbit(100009013) eukaryotic translation initiation factor 2-alpha kinase 2
  • domestic cat(101082744) eukaryotic translation initiation factor 2-alpha kinase 2
  • sheep(101121673) eukaryotic translation initiation factor 2-alpha kinase 2
  • dog(611397) eukaryotic translation initiation factor 2-alpha kinase 2
  • naked mole-rat(101724844) eukaryotic translation initiation factor 2-alpha kinase 2
  • Horse(100147679) eukaryotic translation initiation factor 2-alpha kinase 2
  • chicken(395147) eukaryotic translation initiation factor 2-alpha kinase 2
  • cow(347700) eukaryotic translation initiation factor 2-alpha kinase 2

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Antibodies

產品編號
描述
物種活性
應用
Anti-phospho-PKR (pThr446) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
Anti-PKR antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

immunohistochemistry

western blot
抗磷酸化PKR (Thr446) 抗体, Upstate®, from rabbit,
物種活性
human
應用
western blot
Anti-PKR (ET-20) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
human
應用
microarray
western blot
ANTI-EIF2AK2 antibody produced in mouse, clone 2C2, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence

western blot

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human EIF2AK2,
物種
human