DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
同義詞:
物種:
Human DNMT3L (29947), Mouse Dnmt3l (54427), Rat Dnmt3l (309680), dog DNMT3L (608536), domestic cat DNMT3L (101091300), cow DNMT3L (613785), sheep DNMT3L (101102451), naked mole-rat Dnmt3l (101719207), domestic guinea pig Dnmt3l (100729608), Horse DNMT3L (100050680)
UniProtKB ID:
基因 ID:
- Human(29947) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
- Mouse(54427) DNA (cytosine-5-)-methyltransferase 3-like
- Rat(309680) DNA (cytosine-5-)-methyltransferase 3-like
- dog(608536) DNA (cytosine-5-)-methyltransferase 3-like
- domestic cat(101091300) DNA (cytosine-5-)-methyltransferase 3-like
- cow(613785) DNA (cytosine-5-)-methyltransferase 3-like
- sheep(101102451) DNA (cytosine-5-)-methyltransferase 3-like
- naked mole-rat(101719207) DNA (cytosine-5-)-methyltransferase 3-like
- domestic guinea pig(100729608) DNA (cytosine-5-)-methyltransferase 3-like
- Horse(100050680) DNA (cytosine-5-)-methyltransferase 3-like
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Antibodies
產品編號
描述
物種活性
應用
Proteins
產品編號
描述
物種
DNMT3A/DNMT3L，活性，人, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
物種
human