跳轉至內容
Merck

DCX

doublecortin

同義詞:
DBCN, DC, LISX, SCLH, XLIS
物種:
Human DCX (1641), Mouse Dcx (13193), Rat Dcx (84394), chicken DCX (374242), dog DCX (612950), domestic cat DCX (494212), cow DCX (787968), Horse DCX (100058909), sheep DCX (101109861), naked mole-rat Dcx (101711611)
UniProtKB ID:
O43602, A6NFY6, A9Z1V8, D3DUY8, D3DUY9, D3DUZ0, O43911, Q5JYZ5
基因 ID:
  • Human(1641) Summary: This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010]
  • Mouse(13193) doublecortin
  • Rat(84394) doublecortin
  • chicken(374242) doublecortin
  • dog(612950) doublecortin
  • domestic cat(494212) doublecortin
  • cow(787968) doublecortin
  • Horse(100058909) doublecortin
  • sheep(101109861) doublecortin
  • naked mole-rat(101711611) doublecortin
  • domestic guinea pig(100713827) doublecortin

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Antibodies

產品編號
描述
物種活性
應用
MABN707
抗-DCX抗体，克隆2G5, clone 2G5, from mouse,
物種活性
human, mouse
應用
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
AV41333
Anti-DCX (AB1) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot
SAB2501666
Anti-DCX antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB2502091
Anti-Dcx antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
western blot
WH0001641M1
Monoclonal Anti-DCX antibody produced in mouse, clone 1G12, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence
western blot