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Merck

CES1

carboxylesterase 1

同義詞:
ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1
物種:
UniProtKB ID:
基因 ID:
  • Human(1066) Summary: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
  • naked mole-rat(101726140) carboxylesterase 1
  • cow(512098) carboxylesterase 1 (monocyte/macrophage serine esterase 1)
  • domestic cat(493774) carboxylesterase 1
  • dog(403643) carboxylesterase 1
  • chicken(415786) carboxylesterase 1 (monocyte/macrophage serine esterase 1)

Custom & Knockdown Gene Products

Antibodies

產品編號
描述
物種活性
應用
Anti-CES1 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
物種活性
human
應用
western blot
Anti-CES1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
2-癸酮, 98%,
物種
human
1-苯基-1,2-丙二酮, 98%, FG,
物種
human
乙酰丙酮, ReagentPlus®, ≥99%,
物種
human
2,2-二甲氧基-苯基苯乙酮, 99%,
物種
human
2,3-丁二酮, 97%,
物種
human