CCND3
cyclin D3
Human CCND3 (896), Mouse Ccnd3 (12445), Rat Ccnd3 (25193), domestic cat CCND3 (101101311), Domestic Rabbit CCND3 (100009038), domestic guinea pig Ccnd3 (100718785), naked mole-rat Ccnd3 (101708062), sheep CCND3 (100147798), dog CCND3 (608847), chicken CCND3 (419928) ...更多
- Human(896) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
- Mouse(12445) cyclin D3
- Rat(25193) cyclin D3
- domestic cat(101101311) cyclin D3
- Domestic Rabbit(100009038) cyclin D3
- domestic guinea pig(100718785) cyclin D3
- naked mole-rat(101708062) cyclin D3
- sheep(100147798) cyclin D3
- dog(608847) cyclin D3
- chicken(419928) cyclin D3
- cow(540547) cyclin D3
- Zebrafish(449996) cyclin D3
Custom & Knockdown Gene Products
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Custom Gene Products
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Antibodies
Anti-Cyclin D3 antibody produced in rabbit, affinity isolated antibody,
human, mouse, rat
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
CDK4/CyclinD3, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human