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Merck

CCND3

cyclin D3

同義詞:
物種:
UniProtKB ID:
基因 ID:
  • Human(896) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
  • Mouse(12445) cyclin D3
  • Rat(25193) cyclin D3
  • domestic cat(101101311) cyclin D3
  • Domestic Rabbit(100009038) cyclin D3
  • domestic guinea pig(100718785) cyclin D3
  • naked mole-rat(101708062) cyclin D3
  • sheep(100147798) cyclin D3
  • dog(608847) cyclin D3
  • chicken(419928) cyclin D3
  • cow(540547) cyclin D3
  • Zebrafish(449996) cyclin D3

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Antibodies

產品編號
描述
物種活性
應用
Anti-Cyclin D3 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry

western blot

Proteins

產品編號
描述
物種
CDK4/CyclinD3, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human