AR
androgen receptor
同義詞:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
物種:
Human AR (367), Mouse Ar (11835), Rat Ar (24208), fruit fly ar (44503), Zebrafish ar (100005148), chicken AR (422165), dog AR (403588), domestic cat AR (101081787), domestic cat AR (751827), Horse AR (100033980) ...更多
UniProtKB ID:
基因 ID:
- Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11835) androgen receptor
- Rat(24208) androgen receptor
- fruit fly(44503) abdomen rotatum
- Zebrafish(100005148) androgen receptor
- chicken(422165) androgen receptor
- dog(403588) androgen receptor
- domestic cat(101081787) androgen receptor
- domestic cat(751827) androgen receptor
- Horse(100033980) androgen receptor
- cow(280675) androgen receptor
- sheep(443042) androgen receptor
- Goat(100860827) androgen receptor
- Domestic Rabbit(100009193) androgen receptor
- domestic guinea pig(100726891) androgen receptor
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Small Molecule - Activator
Small Molecule - Agonist
產品編號
描述
物種
睾酮 溶液, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
美雄酮 溶液, 1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
Small Molecule - Antagonist
Antibodies
產品編號
描述
物種活性
應用
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal, clone SP242, recombinant, expressed in proprietary host, affinity isolated antibody,
物種活性
dog, human, mouse, pig, rabbit, rat
應用
immunohistochemistry
Anti-phospho-Androgen Receptor (Ser81) Antibody, rabbit monoclonal, culture supernatant, Upstate®,
物種活性
human
應用
western blot
Anti-Androgen Receptor antibody, Rabbit monoclonal, clone SP107, recombinant, expressed in proprietary host, affinity isolated antibody,
物種活性
dog, human, mouse, pig, rat
應用
immunohistochemistry
Anti-Androgen Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
ChIP
ELISA
immunohistochemistry
western blot
ELISA
immunohistochemistry
western blot
Anti-Androgen Receptor antibody produced in rabbit, affinity isolated antibody,
物種活性
human
應用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Blocker
產品編號
描述
物種
Small Molecule - Inhibitor
Small Molecule - Ligand
Proteins
esiRNA
產品編號
描述
物種