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Merck

APLP2

amyloid beta (A4) precursor-like protein 2

同義詞:
APLP-2, APPH, APPL2, CDEBP
物種:
UniProtKB ID:
基因 ID:
  • Human(334) Summary: This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
  • Mouse(11804) amyloid beta (A4) precursor-like protein 2
  • Rat(64312) amyloid beta (A4) precursor-like protein 2
  • naked mole-rat(101696833) amyloid beta (A4) precursor-like protein 2
  • Horse(100068170) amyloid beta (A4) precursor-like protein 2
  • Horse(100072668) amyloid beta (A4) precursor-like protein 2
  • domestic cat(101095518) amyloid beta (A4) precursor-like protein 2
  • sheep(101119774) amyloid beta (A4) precursor-like protein 2
  • domestic guinea pig(100713756) amyloid beta (A4) precursor-like protein 2
  • Domestic Rabbit(100358231) amyloid beta (A4) precursor-like protein 2
  • chicken(419727) amyloid beta (A4) precursor-like protein 2
  • Zebrafish(796801) amyloid beta (A4) precursor-like protein 2
  • cow(785005) amyloid beta (A4) precursor-like protein 2
  • dog(479393) amyloid beta (A4) precursor-like protein 2

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Antibodies

產品編號
描述
物種活性
應用
Monoclonal Anti-APLP2 antibody produced in mouse, clone 4B5, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
Anti-APLP2 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
Anti-APLP2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
western blot