跳轉至內容
Merck

ANTXR1

anthrax toxin receptor 1

同義詞:
ATR, GAPO, TEM8
物種:
UniProtKB ID:
基因 ID:
  • Human(84168) Summary: This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
  • Mouse(69538) anthrax toxin receptor 1
  • Rat(362393) anthrax toxin receptor 1
  • naked mole-rat(101701494) anthrax toxin receptor 1
  • domestic guinea pig(100728514) anthrax toxin receptor 1
  • sheep(101108204) anthrax toxin receptor 1
  • Domestic Rabbit(100357637) anthrax toxin receptor 1
  • cow(616010) anthrax toxin receptor 1
  • domestic cat(101092930) anthrax toxin receptor 1
  • Horse(100061334) anthrax toxin receptor 1
  • dog(612601) anthrax toxin receptor 1
  • chicken(428199) anthrax toxin receptor 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

產品編號
描述
物種活性
應用
Anti-TEM8/Anthrax Toxin Receptor 1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
Anti-ANTXR1 antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
應用
western blot