AIRE
autoimmune regulator
同義詞:
AIRE1, APECED, APS1, APSI, PGA1
物種:
Human AIRE (326), Mouse Aire (11634), Rat Aire (294328), domestic guinea pig Aire (100729880), sheep AIRE (101102698), cow AIRE (784775), Zebrafish aire (100007662), chicken AIRE (429666), dog AIRE (487796), naked mole-rat Aire (101725873)
UniProtKB ID:
基因 ID:
- Human(326) Summary: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
- Mouse(11634) autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
- Rat(294328) autoimmune regulator
- domestic guinea pig(100729880) autoimmune regulator
- sheep(101102698) autoimmune regulator
- cow(784775) autoimmune regulator
- Zebrafish(100007662) autoimmune regulator
- chicken(429666) autoimmune regulator
- dog(487796) autoimmune regulator
- naked mole-rat(101725873) autoimmune regulator
- domestic cat(101091039) autoimmune regulator
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Antibodies
產品編號
描述
物種活性
應用
Anti-AIRE (Isoforms 1 and 2) (AB2) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot