ACTN4
actinin, alpha 4
同義詞:
ACTININ-4, FSGS, FSGS1
物種:
Human ACTN4 (81), Mouse Actn4 (60595), Rat Actn4 (63836), Zebrafish actn4 (322221), naked mole-rat Actn4 (101710271), domestic cat ACTN4 (101093978), dog ACTN4 (484526), chicken ACTN4 (396024), cow ACTN4 (522269), domestic guinea pig Actn4 (100733111)
UniProtKB ID:
基因 ID:
- Human(81) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
- Mouse(60595) actinin alpha 4
- Rat(63836) actinin alpha 4
- Zebrafish(322221) actinin, alpha 4
- naked mole-rat(101710271) actinin, alpha 4
- domestic cat(101093978) actinin, alpha 4
- dog(484526) actinin, alpha 4
- chicken(396024) actinin, alpha 4
- cow(522269) actinin, alpha 4
- domestic guinea pig(100733111) actinin, alpha 4
- sheep(101111737) actinin, alpha 4
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Antibodies
產品編號
描述
物種活性
應用
Monoclonal Anti-ACTN4 antibody produced in mouse, clone 4D10, purified immunoglobulin, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Alpha Actinin-4 antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM287, purified immunoglobulin,
物種活性
human
應用
immunohistochemistry
western blot
western blot
Anti-ACTN4 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
應用
immunohistochemistry
western blot
western blot
Proteins
產品編號
描述
物種
α-Actinin from chicken gizzard, ~80% α-actinin basis (SDS-PAGE), ammonium sulfate suspension,
物種
mouse, chicken, rat, human