跳轉至內容
Merck

ABCC1

ATP-binding cassette, sub-family C (CFTR/MRP), member 1

同義詞:
ABC29, ABCC, GS-X, MRP, MRP1
物種:
UniProtKB ID:
基因 ID:
  • Human(4363) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]
  • Mouse(17250) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Rat(24565) ATP-binding cassette, subfamily C (CFTR/MRP), member 1
  • naked mole-rat(101725452) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • sheep(101110991) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • domestic cat(101101279) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Horse(791240) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • chicken(395416) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Domestic Rabbit(100345841) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • Zebrafish(100002010) ATP-binding cassette, sub-family C, member 1
  • cow(281588) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • domestic guinea pig(100734674) ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • dog(403453) ATP-binding cassette, sub-family C (CFTR/MRP), member 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

產品編號
描述
物種活性
應用
Anti-MRP1 Antibody, clone QCRL-1, clone QCRL-1, Chemicon®, from mouse,
物種活性
human
應用
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-Multi-Drug Resistance Related Protein Antibody, clone MRPm6, culture supernatant, clone MRPm6, Chemicon®,
物種活性
human
應用
flow cytometry
immunohistochemistry

western blot
Anti-MRP1 antibody,Mouse monoclonal, clone QCRL-1, purified from hybridoma cell culture,
物種活性
human
應用
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-MRP1 Antibody, clone MRPm5, clone MRPm5, Chemicon®, from mouse,
物種活性
human
應用
flow cytometry
immunohistochemistry

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
氯喹 二磷酸盐, powder or crystals, 98.5-101.0% (EP),
物種
human

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human ABCC1,
物種
human