UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3
Synonyms:
UDPGT, UDPGT 1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C
Species:
UniProtKB ID:
Gene ID:
- Human(54659) Summary: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. Substrates of this enzyme include estrone, 2-hydroxyestrone, and metabolites of benzo alpha-pyrene. [provided by RefSeq, Jul 2008]
- Rat(396551) UDP glycosyltransferase 1 family, polypeptide A3
- sheep(100534645) UDP glucuronosyltransferase 1 family, polypeptide A3
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-UGT1A3 antibody produced in mouse, clone 1C10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot