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Merck

TNFRSF13C

tumor necrosis factor receptor superfamily, member 13C

Synonyms:
BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin
Species:
Human TNFRSF13C (115650), Mouse Tnfrsf13c (72049), Rat Tnfrsf13c (500910), chicken TNFRSF13C (417983), dog TNFRSF13C (607785), Horse TNFRSF13C (100070724), domestic guinea pig Tnfrsf13c (100713376), naked mole-rat Tnfrsf13c (101700523), domestic cat TNFRSF13C (101090370), sheep TNFRSF13C (101104901)
UniProtKB ID:
Q96RJ3
Gene ID:
  • Human(115650) Summary: B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
  • Mouse(72049) tumor necrosis factor receptor superfamily, member 13c
  • Rat(500910) tumor necrosis factor receptor superfamily, member 13c
  • chicken(417983) tumor necrosis factor receptor superfamily, member 13C
  • dog(607785) tumor necrosis factor receptor superfamily, member 13C
  • Horse(100070724) tumor necrosis factor receptor superfamily, member 13C
  • domestic guinea pig(100713376) tumor necrosis factor receptor superfamily, member 13C
  • naked mole-rat(101700523) tumor necrosis factor receptor superfamily, member 13C
  • domestic cat(101090370) tumor necrosis factor receptor superfamily, member 13C
  • sheep(101104901) tumor necrosis factor receptor superfamily, member 13C

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Proteins

Product Number
Description
Species
SRP3009
BAFF Receptor human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture,
Species
human