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THAP1

THAP domain containing, apoptosis associated protein 1

Synonyms:
DYT6
Species:
Human THAP1 (55145), Mouse Thap1 (73754), Rat Thap1 (306547), naked mole-rat Thap1 (101703767), domestic guinea pig Thap1 (100719440), sheep THAP1 (101119790), cow THAP1 (538615), dog THAP1 (475569), domestic cat THAP1 (101097720), Zebrafish thap1 (692315)
UniProtKB ID:
Q9NVV9, A6NCB6, D3DSY5, H9KV49, Q53FQ1, Q6IA99
Gene ID:
  • Human(55145) Summary: The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(73754) THAP domain containing, apoptosis associated protein 1
  • Rat(306547) THAP domain containing, apoptosis associated protein 1
  • naked mole-rat(101703767) THAP domain containing, apoptosis associated protein 1
  • domestic guinea pig(100719440) THAP domain containing, apoptosis associated protein 1
  • sheep(101119790) THAP domain containing, apoptosis associated protein 1
  • cow(538615) THAP domain containing, apoptosis associated protein 1
  • dog(475569) THAP domain containing, apoptosis associated protein 1
  • domestic cat(101097720) THAP domain containing, apoptosis associated protein 1
  • Zebrafish(692315) THAP domain containing, apoptosis associated protein 1
  • chicken(431620) THAP domain containing, apoptosis associated protein 1

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