TGFBR1
transforming growth factor, beta receptor 1
Synonyms:
AAT5, ACVRLK4, ALK-5, ALK5, LDS1A, LDS2A, MSSE, SKR4, TGFR-1
Species:
Human TGFBR1 (7046), Mouse Tgfbr1 (21812), Rat Tgfbr1 (29591), chicken TGFBR1 (374094), dog TGFBR1 (481628), sheep TGFBR1 (554326), cow TGFBR1 (282382), domestic cat TGFBR1 (101094057), naked mole-rat Tgfbr1 (101718090), domestic guinea pig Tgfbr1 (100715237)
UniProtKB ID:
Gene ID:
- Human(7046) Summary: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(21812) transforming growth factor, beta receptor I
- Rat(29591) transforming growth factor, beta receptor 1
- chicken(374094) transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa)
- dog(481628) transforming growth factor, beta receptor 1
- sheep(554326) transforming growth factor, beta receptor 1
- cow(282382) transforming growth factor, beta receptor 1
- domestic cat(101094057) transforming growth factor, beta receptor 1
- naked mole-rat(101718090) transforming growth factor, beta receptor 1
- domestic guinea pig(100715237) transforming growth factor, beta receptor 1
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Antibodies
Product Number
Description
Species Reactivity
Application
ANTI-TGF BETA RECEPTOR I (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-TGFBR1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, rat
Application
ELISA
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Anti-TGF β Receptor I antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-TGFBR1 (center) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TGF-beta Receptor Antibody, type I, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, human, mouse, porcine, rat
Application
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Proteins
Product Number
Description
Species
TGFBR-1 Protein, active, 10 µg, Active, N-terminal GST-tagged, recombinant, human TGFBR1 amino acids 200–end containing a T204D mutation, expressed by baculovirus in Sf21 insect cells. Purified using glutathione agarose. For use in Kinase Assays.,
Species
human
esiRNA
Product Number
Description
Species