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Merck

SPTBN1

spectrin, beta, non-erythrocytic 1

Synonyms:
ELF, SPTB2, betaSpII
Species:
Human SPTBN1 (6711), Mouse Sptbn1 (20742), Rat Sptbn1 (305614), cow SPTBN1 (526027), Horse SPTBN1 (100052695), domestic cat SPTBN1 (101090509), naked mole-rat Sptbn1 (101714374), domestic guinea pig Sptbn1 (100712783), dog SPTBN1 (403743), chicken SPTBN1 (421216)
UniProtKB ID:
Q01082, B2RP63, O60837, Q16057, Q53R99, Q59ER3, Q8IX99
Gene ID:
  • Human(6711) Summary: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(20742) spectrin beta, non-erythrocytic 1
  • Rat(305614) spectrin, beta, non-erythrocytic 1
  • cow(526027) spectrin, beta, non-erythrocytic 1
  • Horse(100052695) spectrin, beta, non-erythrocytic 1
  • domestic cat(101090509) spectrin, beta, non-erythrocytic 1
  • naked mole-rat(101714374) spectrin, beta, non-erythrocytic 1
  • domestic guinea pig(100712783) spectrin, beta, non-erythrocytic 1
  • dog(403743) spectrin, beta, non-erythrocytic 1
  • chicken(421216) spectrin, beta, non-erythrocytic 1
  • Zebrafish(100316998) spectrin, beta, non-erythrocytic 1

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Antibodies

Product Number
Description
Species Reactivity
Application
MABN1727
Anti-Beta-IV spectrin Antibody, clone N393/76, clone N393/76, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
S1515
Anti-Spectrin antibody produced in rabbit, whole antiserum,
Species Reactivity
human
Application
western blot