SIPA1
signal-induced proliferation-associated 1
Synonyms:
SPA1
Species:
Human SIPA1 (6494), Mouse Sipa1 (20469), Rat Sipa1 (361710), domestic guinea pig Sipa1 (100731279), naked mole-rat Sipa1 (101717091), sheep SIPA1 (101101937), domestic cat SIPA1 (101099149), dog SIPA1 (483730), cow SIPA1 (508234)
UniProtKB ID:
Gene ID:
- Human(6494) Summary: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]
- Mouse(20469) signal-induced proliferation associated gene 1
- Rat(361710) signal-induced proliferation-associated 1
- domestic guinea pig(100731279) signal-induced proliferation-associated 1
- naked mole-rat(101717091) signal-induced proliferation-associated 1
- sheep(101101937) signal-induced proliferation-associated 1
- domestic cat(101099149) signal-induced proliferation-associated 1
- dog(483730) signal-induced proliferation-associated 1
- cow(508234) signal-induced proliferation-associated 1
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