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Merck

SIM1

single-minded homolog 1 (Drosophila)

Synonyms:
bHLHe14
Species:
Human SIM1 (6492), Mouse Sim1 (20464), Rat Sim1 (309888), dog SIM1 (481937), sheep SIM1 (101123562), Domestic Rabbit SIM1 (100357074), chicken SIM1 (396129), naked mole-rat Sim1 (101711620), cow SIM1 (537223), domestic guinea pig Sim1 (100732546) ...More
UniProtKB ID:
P81133, Q5TDP7
Gene ID:
  • Human(6492) Summary: SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome. [provided by RefSeq, Jul 2008]
  • Mouse(20464) single-minded homolog 1 (Drosophila)
  • Rat(309888) single-minded homolog 1 (Drosophila)
  • dog(481937) single-minded homolog 1 (Drosophila)
  • sheep(101123562) single-minded homolog 1 (Drosophila)
  • Domestic Rabbit(100357074) single-minded homolog 1 (Drosophila)
  • chicken(396129) single-minded homolog 1 (Drosophila)
  • naked mole-rat(101711620) single-minded homolog 1 (Drosophila)
  • cow(537223) single-minded homolog 1 (Drosophila)
  • domestic guinea pig(100732546) single-minded homolog 1 (Drosophila)
  • domestic cat(101086396) single-minded homolog 1 (Drosophila)
  • Horse(100066172) single-minded homolog 1 (Drosophila)

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Antibodies

Product Number
Description
Species Reactivity
Application
AB4144
Anti-SIM1 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry