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Merck

SDHB

succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

Synonyms:
CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP
Species:
UniProtKB ID:
Gene ID:
  • Human(6390) Summary: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq, Jul 2008]
  • Mouse(67680) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • Rat(298596) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • Horse(100050091) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • Zebrafish(562149) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • chicken(100859720) succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial-like
  • fruit fly(35590) Succinate dehydrogenase B
  • domestic guinea pig(100728812) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • naked mole-rat(101720891) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • cow(286840) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • sheep(101108729) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • Domestic Rabbit(100328585) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • dog(478217) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • domestic cat(751617) succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SDHB antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-SDHB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot
Anti-SDHB Antibody, clone 10C5.1, clone 10C5.1, from mouse,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
Monoclonal Anti-SDHB antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0347, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Kits

Product Number
Description
Species
Succinate Dehydrogenase Assay Kit, Sufficient for 100 Colorimetric tests,
Species
rat, human, mouse