RNF8
ring finger protein 8, E3 ubiquitin protein ligase
Synonyms:
hRNF8
Species:
Human RNF8 (9025), Mouse Rnf8 (58230), Rat Rnf8 (361815), naked mole-rat Rnf8 (101703952), domestic guinea pig Rnf8 (100725403), sheep RNF8 (101103680), chicken RNF8 (421435), domestic cat RNF8 (101082654), dog RNF8 (481775), Zebrafish rnf8 (404050)
UniProtKB ID:
Gene ID:
- Human(9025) Summary: The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
- Mouse(58230) ring finger protein 8
- Rat(361815) ring finger protein 8, E3 ubiquitin protein ligase
- naked mole-rat(101703952) ring finger protein 8, E3 ubiquitin protein ligase
- domestic guinea pig(100725403) ring finger protein 8, E3 ubiquitin protein ligase
- sheep(101103680) ring finger protein 8, E3 ubiquitin protein ligase
- chicken(421435) ring finger protein 8, E3 ubiquitin protein ligase
- domestic cat(101082654) ring finger protein 8, E3 ubiquitin protein ligase
- dog(481775) ring finger protein 8, E3 ubiquitin protein ligase
- Zebrafish(404050) ring finger protein 8, E3 ubiquitin protein ligase
- cow(515933) ring finger protein 8
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RNF8 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, horse, human, mouse, pig, rat
Application
immunohistochemistry
western blot
western blot