PPP1R8
protein phosphatase 1, regulatory subunit 8
Synonyms:
ARD-1, ARD1, NIPP-1, NIPP1, PRO2047
Species:
Human PPP1R8 (5511), Mouse Ppp1r8 (100336), Rat Ppp1r8 (313030), chicken PPP1R8 (419564), dog PPP1R8 (487340), domestic guinea pig Ppp1r8 (100722083), domestic cat PPP1R8 (101084555), Zebrafish ppp1r8 (566830), naked mole-rat Ppp1r8 (101707477), sheep PPP1R8 (101105555) ...More
UniProtKB ID:
Gene ID:
- Human(5511) Summary: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]
- Mouse(100336) protein phosphatase 1, regulatory (inhibitor) subunit 8
- Rat(313030) protein phosphatase 1, regulatory subunit 8
- chicken(419564) protein phosphatase 1, regulatory subunit 8
- dog(487340) protein phosphatase 1, regulatory subunit 8
- domestic guinea pig(100722083) protein phosphatase 1, regulatory subunit 8
- domestic cat(101084555) protein phosphatase 1, regulatory subunit 8
- Zebrafish(566830) protein phosphatase 1, regulatory (inhibitor) subunit 8
- naked mole-rat(101707477) protein phosphatase 1, regulatory subunit 8
- sheep(101105555) protein phosphatase 1, regulatory subunit 8
- cow(282319) protein phosphatase 1, regulatory subunit 8
- Horse(100056729) protein phosphatase 1, regulatory subunit 8
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