POU5F1
POU class 5 homeobox 1
Synonyms:
OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4
Species:
Human POU5F1 (5460), Mouse Pou5f1 (18999), Rat Pou5f1 (294562), sheep POU5F1 (100302349), cow POU5F1 (282316), domestic cat POU5F1 (100174788), dog POU5F1 (481709), Goat POU5F1 (100861237), domestic guinea pig Pou5f1 (100724951), Domestic Rabbit POU5F1 (100101567)
UniProtKB ID:
Gene ID:
- Human(5460) Summary: This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq, Mar 2010]
- Mouse(18999) POU domain, class 5, transcription factor 1
- Rat(294562) POU class 5 homeobox 1
- sheep(100302349) POU class 5 homeobox 1
- cow(282316) POU class 5 homeobox 1
- domestic cat(100174788) POU class 5 homeobox 1
- dog(481709) POU class 5 homeobox 1
- Goat(100861237) POU class 5 homeobox 1
- domestic guinea pig(100724951) POU class 5 homeobox 1
- Domestic Rabbit(100101567) POU class 5 homeobox 1
- naked mole-rat(101722299) POU class 5 homeobox 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-POU5F1 (Oct4) antibody produced in mouse, ~1.0 mg/mL, clone PF-29, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-OCT3 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Oct-4 Antibody, clone 10H11.2, Alexa Fluor™ 488 conjugate, clone 10H11.2, from mouse, ALEXA FLUOR™ 488,
Species Reactivity
human
Application
flow cytometry
immunocytochemistry
immunocytochemistry
Anti-Oct-4 Antibody, Chemicon®, from rabbit,
Species Reactivity
human, mouse
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-OCT4/POU5F1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
western blot
esiRNA
Product Number
Description
Species