POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
Synonyms:
POLR2, POLRA, RPB1, RPBh1, RPO2, RPOL2, RpIILS, hRPB220, hsRPB1
Species:
Human POLR2A (5430), Mouse Polr2a (20020), Rat Polr2a (363633), cow POLR2A (282312), naked mole-rat Polr2a (101725588), dog POLR2A (479483), Zebrafish polr2a (553347), sheep POLR2A (100144762), domestic cat POLR2A (101098500), domestic guinea pig Polr2a (100734232)
UniProtKB ID:
Gene ID:
- Human(5430) Summary: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
- Mouse(20020) polymerase (RNA) II (DNA directed) polypeptide A
- Rat(363633) polymerase (RNA) II (DNA directed) polypeptide A
- cow(282312) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- naked mole-rat(101725588) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- dog(479483) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- Zebrafish(553347) polymerase (RNA) II (DNA directed) polypeptide A
- sheep(100144762) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- domestic cat(101098500) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
- domestic guinea pig(100734232) polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
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Antibodies
Product Number
Description
Species Reactivity
Application
Goat anti-RNA Polymerase II Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
western blot
Monoclonal Anti-phospho-RNA polymerase II CTD (pSer2) antibody produced in rat, clone 3E7C7, purified from hybridoma cell culture,
Species Reactivity
Application
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-RNA Polymerase II Antibody, clone ARNA-3, ascites fluid, clone ARNA-3, Chemicon®,
Species Reactivity
drosophila, human, kangaroo
Application
immunohistochemistry
western blot
western blot
Anti-RNA Polymerase II Antibody, CTD Antibody, clone 8WG16, clone 8WG16, from mouse,
Species Reactivity
human, yeast
Application
dot blot
immunoprecipitation (IP)
inhibition assay
western blot
immunoprecipitation (IP)
inhibition assay
western blot
Monoclonal Anti-POLR2A, (N-terminal) antibody produced in mouse, clone IF17, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Proteins
esiRNA
Product Number
Description
Species