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Merck

MED17

mediator complex subunit 17

Synonyms:
CRSP6, CRSP77, DRIP80, TRAP80
Species:
UniProtKB ID:
Gene ID:
  • Human(9440) Summary: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq, Jul 2008]
  • Mouse(234959) mediator complex subunit 17
  • Rat(300367) mediator complex subunit 17
  • chicken(419000) mediator complex subunit 17
  • domestic guinea pig(100720611) mediator complex subunit 17
  • fruit fly(42175) Mediator complex subunit 17
  • naked mole-rat(101706308) mediator complex subunit 17
  • Zebrafish(567560) mediator complex subunit 17
  • cow(541303) mediator complex subunit 17
  • sheep(101106726) mediator complex subunit 17
  • domestic cat(101082432) mediator complex subunit 17
  • dog(476769) mediator complex subunit 17

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