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Merck

KCNAB1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

Synonyms:
AKR6A3, KCNA1B, KV-BETA-1, Kvb1.3, hKvBeta3, hKvb3
Species:
UniProtKB ID:
Gene ID:
  • Human(7881) Summary: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes three distinct isoforms which are encoded by three alternatively spliced transcript variants of this gene. These three isoforms are beta subunits, which form heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subunits. [provided by RefSeq, Jul 2008]
  • Mouse(16497) potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • Rat(29737) potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • cow(526133) potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • chicken(395730) potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • domestic cat(101086170) potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • Zebrafish(541540) potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • sheep(101110988) potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • Horse(100050434) potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • domestic guinea pig(100725410) potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • dog(612006) potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • Domestic Rabbit(100328569) potassium voltage-gated channel, shaker-related subfamily, beta member 1
  • naked mole-rat(101720455) potassium voltage-gated channel, shaker-related subfamily, beta member 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KCNAB1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot