JAM3
junctional adhesion molecule 3
Synonyms:
JAM-2, JAM-3, JAM-C, JAMC
Species:
Human JAM3 (83700), Mouse Jam3 (83964), Rat Jam3 (315509), naked mole-rat Jam3 (101707307), domestic guinea pig Jam3 (100735476), sheep JAM3 (101117375), domestic cat JAM3 (101097016), cow JAM3 (513412), dog JAM3 (489271), chicken JAM3 (419736)
UniProtKB ID:
Gene ID:
- Human(83700) Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
- Mouse(83964) junction adhesion molecule 3
- Rat(315509) junctional adhesion molecule 3
- naked mole-rat(101707307) junctional adhesion molecule 3
- domestic guinea pig(100735476) junctional adhesion molecule 3
- sheep(101117375) junctional adhesion molecule 3
- domestic cat(101097016) junctional adhesion molecule 3
- cow(513412) junctional adhesion molecule 3
- dog(489271) junctional adhesion molecule 3
- chicken(419736) junctional adhesion molecule 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-JAM3 antibody produced in mouse, clone 1D3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-JAM3 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot