IL10RA
interleukin 10 receptor, alpha
Synonyms:
CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R
Species:
Human IL10RA (3587), Mouse Il10ra (16154), Rat Il10ra (117539), sheep IL10RA (101120946), domestic guinea pig Il10ra (100727507), dog IL10RA (610823), naked mole-rat Il10ra (101706532), Zebrafish il10ra (777651), domestic cat IL10RA (101087601), cow IL10RA (513478)
UniProtKB ID:
Gene ID:
- Human(3587) Summary: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
- Mouse(16154) interleukin 10 receptor, alpha
- Rat(117539) interleukin 10 receptor, alpha
- sheep(101120946) interleukin 10 receptor, alpha
- domestic guinea pig(100727507) interleukin 10 receptor, alpha
- dog(610823) interleukin 10 receptor, alpha
- naked mole-rat(101706532) interleukin 10 receptor, alpha
- Zebrafish(777651) interleukin 10 receptor, alpha
- domestic cat(101087601) interleukin 10 receptor, alpha
- cow(513478) interleukin 10 receptor, alpha
- chicken(419771) interleukin 10 receptor, alpha
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-IL-10R α antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-Interleukin-10 Receptor α antibody produced in mouse, clone 37607, purified immunoglobulin, lyophilized powder,
Species Reactivity
human
Application
neutralization