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Merck

HLA-DOA

major histocompatibility complex, class II, DO alpha

Synonyms:
HLA-DNA, HLA-DZA, HLADZ
Species:
Human HLA-DOA (3111)
UniProtKB ID:
P06340, Q58HU0, Q58HU1, Q5STC7, Q9TQC6, Q9TQC7, Q9TQC8, Q9TQC9
Gene ID:
  • Human(3111) Summary: HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008]

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