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Merck

ESX1

ESX homeobox 1

Synonyms:
ESX1L, ESXR1
Species:
UniProtKB ID:
Gene ID:
  • Human(80712) Summary: This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis. [provided by RefSeq, Jan 2010]
  • Mouse(13984) extraembryonic, spermatogenesis, homeobox 1
  • domestic cat(101082983) ESX homeobox 1
  • cow(616174) ESX homeobox 1
  • domestic guinea pig(101788333) ESX homeobox 1
  • sheep(101118426) ESX homeobox 1
  • naked mole-rat(101715761) ESX homeobox 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ESX1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, mouse
Application
western blot