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Merck

CHP2

calcineurin-like EF-hand protein 2

Synonyms:
Species:
Human CHP2 (63928), Mouse Chp2 (70261), Rat Chp2 (308965), dog CHP2 (489969), domestic cat CHP2 (101089230), domestic guinea pig Chp2 (100722300), cow CHP2 (515280), naked mole-rat Chp2 (101722351), Zebrafish chp2 (327599), sheep CHP2 (101118159)
UniProtKB ID:
O43745
Gene ID:
  • Human(63928) Summary: This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520. [provided by RefSeq, Jul 2013]
  • Mouse(70261) calcineurin-like EF hand protein 2
  • Rat(308965) calcineurin-like EF hand protein 2
  • dog(489969) calcineurin B homologous protein 2
  • domestic cat(101089230) calcineurin-like EF hand protein 2
  • domestic guinea pig(100722300) calcineurin-like EF-hand protein 2
  • cow(515280) calcineurin B homologous protein 2
  • naked mole-rat(101722351) calcineurin-like EF-hand protein 2
  • Zebrafish(327599) calcineurin-like EF hand protein 2
  • sheep(101118159) calcineurin-like EF hand protein 2

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4502725
Anti-CHP2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
SAB4300914
Anti-CHP2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot