CDH4
cadherin 4, type 1, R-cadherin (retinal)
Synonyms:
CAD4, RCAD
Species:
Human CDH4 (1002), Mouse Cdh4 (12561), Rat Cdh4 (114588), naked mole-rat Cdh4 (101726465), domestic guinea pig Cdh4 (100720758), sheep CDH4 (101122716), chicken CDH4 (419222), cow CDH4 (525796), dog CDH4 (100685099), Zebrafish cdh4 (30297)
UniProtKB ID:
Gene ID:
- Human(1002) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
- Mouse(12561) cadherin 4
- Rat(114588) cadherin 4
- naked mole-rat(101726465) cadherin 4, type 1, R-cadherin (retinal)
- domestic guinea pig(100720758) cadherin 4, type 1, R-cadherin (retinal)
- sheep(101122716) cadherin 4, type 1, R-cadherin (retinal)
- chicken(419222) cadherin 4, type 1, R-cadherin (retinal)
- cow(525796) cadherin 4, type 1, R-cadherin (retinal)
- dog(100685099) cadherin 4, type 1, R-cadherin (retinal)
- Zebrafish(30297) cadherin 4, retinal
- domestic cat(101085708) cadherin 4, type 1, R-cadherin (retinal)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CDH4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, mouse, rat
Application
western blot