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Merck

ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

Synonyms:
BCDase, HNAC1, LCDase, N-CDase, NCDase
Species:
Human ASAH2 (56624), Mouse Asah2 (54447), Rat Asah2 (114104), cow ASAH2 (615837), cow ASAH2 (100336736), sheep ASAH2 (101121732), Horse ASAH2 (100071829), domestic cat ASAH2 (101097670), dog ASAH2 (486461), chicken ASAH2 (423679) ...More
UniProtKB ID:
Q9NR71, Q3KNU1, Q5SNT7, Q5SZP6, Q5SZP7, Q5T1D5, Q71ME6
Gene ID:
  • Human(56624) Summary: Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]
  • Mouse(54447) N-acylsphingosine amidohydrolase 2
  • Rat(114104) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • cow(615837) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • cow(100336736) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • sheep(101121732) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • Horse(100071829) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • domestic cat(101097670) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • dog(486461) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • chicken(423679) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • Zebrafish(493602) N-acylsphingosine amidohydrolase 2
  • naked mole-rat(101709668) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • domestic guinea pig(100728346) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • Domestic Rabbit(100357673) N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

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